Publications

Post-2020

12. Y. Qiao*, H. Hayashi, SC. Teo. Chemical Toolbox to Decode the Microbiota Lexicon. Chemistry: an Asian Journal. 2020. DOI: org/10.1002/asia.202000541 (For the special collection of 50th anniversary of SNIC) pdf

Pre-NTU:

11. ZX. Huang, JH. Wang, XL. Xu, HS. Wang, Y. Qiao, WC. Chu, SL. Xu, L. Chai, F. Cottier, N. Pavelka, M. Oosting, LAB. Joosten, M. Netea, CYL. Ng, KP. Leong, P. Kundu, KP. Lam, S. Petterson, Y. Wang. Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity. Nat. Microbiol. 2019, 4, 766–773.

10. MM. Zhang, Y. Qiao‡, EL. Ang, H. Zhao. Using Natural Products for Drug Discovery: the Impact of the Genomic Era. Expert Opin Drug Discov. 2017, 12(5): 475-487.

9. V. Srisuknimit, Y. Qiao‡, K. Schaefer, D. Kahne, S. Walker. Peptidoglycan Cross-Linking Preferences of Staphylococcus aureus Penicillin-Binding Proteins Have Implications for Treating MRSA Infections. J. Am. Chem. Soc. 2017, 139(29): 9791-9794. (equal contribution)

8. Y. Qiao, V. Srisuknimit‡, F. Rubino, K. Schaefer, N. Ruiz, S. Walker, D. Kahne. Lipid II Overproduction Allows Direct Assay of Transpeptidase Inhibition by Beta-lactams. Nat. Chem. Biol. 2017, 13(7): 793-798. (‡ equal contribution)

7. K. Schaefer, L. Matano, Y. Qiao, D. Kahne, S. Walker. In Vitro Reconstitution Demonstrates the Cell Wall Ligase Activity of LCP proteins. Nat. Chem. Biol. 2017, 13(4): 396-401.

6. W. Lee, K. Schaefer, Y. Qiao, V. Srisuknimit, H. Steinmetz, R. Müller, D. Kahne, S. Walker. The Mechanism of Action of Lysobactin. J. Am. Chem. Soc. 2015, 138(1): 100-3.

5. Y. Qiao, MD. Lebar, K. Schirner, K. Schaefer, H. Tsukamoto, D. Kahne, S. Walker. Detection of Lipid-linked Peptidoglycan Precursors by Exploiting an Unexpected Transpeptidase Reaction. J. Am. Chem. Soc. 2014, 136(42): 14678-81.

4. Y. Rebets, T. Lupoli, Y. Qiao, K. Schirner, R. Villet, D. Hooper, D. Kahne, S. Walker. Moenomycin Resistance Mutations in Staphylococcus aureus Reduce Peptidoglycan Chain Length and Cause Aberrant Cell Division. ACS Chem Biol 2014, 9(2): 459-673.

3. K. Fukushima, JPK. Tan, PA. Korevar, Y. Y. Yang, J. Pitera, A. Nelson, H. Maune, DJ. Coady, JE. Frommer, AC. Engler, Y. Huang, K. Xu, Z. Ji, Y. Qiao, W. Fan, L. Li, N. Wiradharma, EW. Meijer, JL. Hedrick. Broad Spectrum Antimicrobial Supramolecular Assemblies with Distinctive Size and Shape. ACS Nano 2012, 6, 9191-9199.

2. Y. Qiao, C. Yang, DJ. Coady, ZY. Ong, JL. Hedrick, Y. Y. Yang. Highly Dynamic Biodegradable Micelles Capable of Lysing Gram-positive and Gram-negative Bacterial Membrane. Biomaterials 2012, 33, 1146-1153

1. Y. Qiao, S. Kumar, W. P. Malachowski. Enatioselective Synthesis of Bicarbocyclic Structures with All Carbon Quaternary Stereocenters through Sequential Cross Metathesis and Intramolecular Rauhut-Currier Reaction. Tet. Lett. 2010, 51, 2636-2638

Patents:

1. C. Gampe, D. Kahne, S. Walker, Y. Qiao, S. East, A. Parkes, M. Southey, J. Hunter, M. Whittaker, A. Arthuis. Entitled: Inhibitors of Bacterial Glycosyl Transferses. International Patent No. PCT/US2016/034587