18. AWR. Ng, L. Li, EWL. Ng, C. Li, Y. Qiao*. Molecular docking reveals critical residues in Candida albicans Cyr1 for peptidoglycan recognition and hyphal growth . ACS Infec Dis. 2023  Accepted. 

17. Y. Liang, Y. Zhao, J. M.C. Kwan, Y. Wang, Y. Qiao*. Escherichia coli has robust regulatory mechanisms against elevated peptidoglycan cleavage by lytic transglycosylases. J. Biol. Chem. 2023  Accepted.

16. J. M. C. Kwan,  Y. Qiao* Mechanistic insights into the activitves of major families of enzymes in bacterial peptidoglycan assembly and breakdown. ChemBioChem,  2023 Jan 30:e202200693. doi: 10.1002/cbic.202200693.

15. L. Li, A. Ng, C. Adamson, H. Hayashi, C. Li, H. Lim, Y. Qiao* Chemoenzymatic Probes Reveal Peptidoglycan Recognition and Uptake Mechanisms in Candida albicans. ACS Chem Biol. 2022. 17, 9, 2538-2550. 

14. C. Li, Y. Liang, Y. Qiao* Messengers of the gut: gut-microbiota derived metabolites on host regulation. Front. Microbiol. 13, 2022.

13. C.T. Tan, X. Xu, Y. Qiao*, Y. Wang*. A peptidoglycan storm caused by β-lactam antibiotic’s action on host microbiota drives Candida albicans infection. Nat Commun 12, 2560 (2021).

12. Y. Qiao*, H. Hayashi, SC. Teo. Chemical Toolbox to Decode the Microbiota Lexicon. Chem Asian J. 2020 Jul 16;15(14):2117-2128. 10.1002/asia.202000541.  (For the special collection of 50th anniversary of SNIC)


11. ZX. Huang, JH. Wang, XL. Xu, HS. Wang, Y. Qiao, WC. Chu, SL. Xu, L. Chai, F. Cottier, N. Pavelka, M. Oosting, LAB. Joosten, M. Netea, CYL. Ng, KP. Leong, P. Kundu, KP. Lam, S. Petterson, Y. Wang. Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity. Nat. Microbiol. 2019, 4, 766–773.

10. MM. Zhang, Y. Qiao‡, EL. Ang, H. Zhao. Using Natural Products for Drug Discovery: the Impact of the Genomic Era. Expert Opin Drug Discov. 2017, 12(5): 475-487. 

9. V. Srisuknimit, Y. Qiao‡, K. Schaefer, D. Kahne, S. Walker. Peptidoglycan Cross-Linking Preferences of Staphylococcus aureus Penicillin-Binding Proteins Have Implications for Treating MRSA Infections. J. Am. Chem. Soc. 2017, 139(29): 9791-9794. (equal contribution) 

8. Y. Qiao, V. Srisuknimit‡, F. Rubino, K. Schaefer, N. Ruiz, S. Walker, D. Kahne. Lipid II Overproduction Allows Direct Assay of Transpeptidase Inhibition by Beta-lactams. Nat. Chem. Biol. 2017, 13(7): 793-798. (‡ equal contribution

7. K. Schaefer, L. Matano, Y. Qiao, D. Kahne, S. Walker. In Vitro Reconstitution Demonstrates the Cell Wall Ligase Activity of LCP proteins. Nat. Chem. Biol. 2017, 13(4): 396-401. 

6. W. Lee, K. Schaefer, Y. Qiao, V. Srisuknimit, H. Steinmetz, R. Müller, D. Kahne, S. Walker. The Mechanism of Action of Lysobactin. J. Am. Chem. Soc. 2015, 138(1): 100-3. 

5. Y. Qiao, MD. Lebar, K. Schirner, K. Schaefer, H. Tsukamoto, D. Kahne, S. Walker. Detection of Lipid-linked Peptidoglycan Precursors by Exploiting an Unexpected Transpeptidase Reaction. J. Am. Chem. Soc. 2014, 136(42): 14678-81. 

4. Y. Rebets, T. Lupoli, Y. Qiao, K. Schirner, R. Villet, D. Hooper, D. Kahne, S. Walker. Moenomycin Resistance Mutations in Staphylococcus aureus Reduce Peptidoglycan Chain Length and Cause Aberrant Cell Division. ACS Chem Biol 2014, 9(2): 459-673. 

3. K. Fukushima, JPK. Tan, PA. Korevar, Y. Y. Yang, J. Pitera, A. Nelson, H. Maune, DJ. Coady, JE. Frommer, AC. Engler, Y. Huang, K. Xu, Z. Ji, Y. Qiao, W. Fan, L. Li, N. Wiradharma, EW. Meijer, JL. Hedrick. Broad Spectrum Antimicrobial Supramolecular Assemblies with Distinctive Size and Shape. ACS Nano 2012,     6, 9191-9199. 

2. Y. Qiao, C. Yang, DJ. Coady, ZY. Ong, JL. Hedrick, Y. Y. Yang. Highly Dynamic Biodegradable Micelles Capable of Lysing Gram-positive and Gram-negative Bacterial Membrane. Biomaterials 2012, 33, 1146-1153 

1. Y. Qiao, S. Kumar, W. P. Malachowski. Enatioselective Synthesis of Bicarbocyclic Structures with All Carbon Quaternary Stereocenters through Sequential Cross Metathesis and Intramolecular Rauhut-Currier Reaction. Tet. Lett. 2010, 51, 2636-2638 


1. C. Gampe, D. Kahne, S. Walker, Y. Qiao, S. East, A. Parkes, M. Southey, J. Hunter, M. Whittaker, A. Arthuis. Entitled: Inhibitors of Bacterial Glycosyl Transferses. International Patent No. PCT/US2016/034587